Cell Model Name Cell Origin Source Repository Data Donor Age Gender FA Genetic Diagnosis Ref Triplet Repeat Allele 1 Triplet Repeat Allele 2 Point Mutation Point Mutation Data Other Tissues Available Other Tissues Detail Passages Primary or Transformed Culture Conditions Line Previously Published Citation iPS Transform Protocol Reprogramming Factors Used Pluripotency Assessment In vitro Pluripotency Assessment In vivo Mycoplasma Karyotype Karyotype Data iPS Culture Conditions Passages GAA Expansion Characterization in iPS Allele Size 1 Allele Size 2 Heterogeneity Neuronal Cell Line NCL Differentiation protocol GAA Expansion Characterization in NCL Allele Size 1 Allele Size 2 Heterogeneity Phenotype Cardiac Cell Line CCL Differentiation protocol GAA Expansion Characterization in CCL Allele Size 1 Allele Size 2 Heterogeneity Phenotype Microarray Analysis Performed Microarray Data Publication Pub Reference Contact Notes
Click to Select hiPS_#2_4078  Fibroblasts  Cell Repository  Coriell, GM04078  Patient  30  Male  Yes  Coriell  430  330  No    Yes  lymphoblasts from Coriell GM04079  Transformed  DMEM, 10% FBS, non-essential amino acids   Yes  viral  OSKMN  Yes  No  Yes  Yes  46, XY, Cell Line Genetics  feeder free, Matrigel and mTeSR1  expansion  860  700  Yes  Yes  neural induction by noggin; neurosphere formation.  no change  Yes  Tuj1+  No          Yes  RNA seq data  mnapiera@mdanderson.org, upolak@mdanderson.org   
Click to Select hiPS_#1_3665  Fibroblasts  Cell Repository  Coriell, GM03665  Patient  13  Female      700  400      No      DMEM, 10% FBS, non-essential amino acids   Yes  viral  OSKMN  Yes  No  Yes  Yes  46, XX Cell Line Genetics  feeder free, Matrigel and mTeSR1  expansion  860  560  Yes  Yes  neural induction by noggin, neurosphere formation  not analyzed      No          No    mnapiera@mdanderson.org; upolak@mdanderson.org   
Click to Select hiPS_#5b_4078  Fibroblasts  Cell Repository  Coriell, GM04078  Patient  30  Male  Yes  Coriell  430  330  No    Yes  lymphobl;asts from Coriell GM04079  Transformed  DMEM, 10% FBS, non-essential amino acids   Yes  viral  OSKMN  Yes    Yes  Yes  46, XY, Cell Line Genetics  feeder free, Matrigel and mTeSR1  not analyzed    No          No          No    mnapiera@mdanderson.org, upolak@mdanderson. org   
Click to Select hiPS_#16_NP  Fibroblasts  Subject    Control  Male  No            10  Transformed  DMEM, 10% FBS, non-essential amino acids       viral  OSKMN  Yes  No  Yes  Yes  46, XY, Cell Line Genetics  feeder free, Matrigel and mTeSR1  22      Yes  neural induction by noggin; neurosphere formation  not analyzed      No          Yes  RNA seq data  mnapiera@mdanderson.org, upolak@mdanderson.org   
Click to Select hiPS_#1_8399  Fibroblasts  Cell Repository  Coriell, GM08399  Control  19  Female  No            Transformed  DMEM, 10% FBS, non-essential amino acids   Yes  viral  OSKMN      Yes  Yes  46, XX Cell Line Genetics   feeder free, Maretgel and mTeSR1      Yes  neural induction by noggin; neurosphere formation  not analyzed      No          No    mnapiera@mdanderson.org, upolak@mdanderson.org   
Click to Select hiPS_#1_8399_cont_sh  Fibroblasts  Cell Repository  Coriell, GM08399  Control  19  Female              Transformed  DMEM, 10% FBS, non-essential amino acids   Yes  viral  OSKMN  Yes  No  Yes  Yes  hiPS_#1_8399, 46, XX Cell Line Genetics  feeder free, Marigel and mTeSR1      No  neural induction by noggin, neurosphere formation  not analyzed      No          No    mnapiera@mdanderson.org, upolak@mdanderson.org   
Click to Select hiPS_#1_8399_FXN_sh2  Fibroblasts  Cell Repository  Coriell, GM08399  Control  19  Female          No    Transformed  DMEM, 10% FBS, non-essential amino acids   Yes  viral  OSKMN  Yes  No  Yes  Yes  hiPS_#1_8399, 46, XX Cell Line Genetics  feeder free, Matrigel and mTeSR1      No          No              mnapiera@mdanderson.org, upolak@mdanderson.org   
Click to Select hiPS_#1_8399_FXN_sh3  Fibroblasts  Cell Repository  Coriell, GM08399  Control  19  Female              Transformed  DMEM, 10% FBS, non-essential amino acids       viral  OSKMN  Yes    Yes  Yes  hiPS_#1_8399, 46, XX Cell Line Genetics  feeder free, Matrigel and mTeSR1      No          No          No    mnapiera@mdanderson.org, upolak@mdanderson.org   
Click to Select 8.2A4R  Fibroblasts  Cell Repository  Coriell, GM03816  Patient  36  Female  Yes  Coriell  380  330  No    No    ~10  Primary  MEM + 1% non-essential AA + 10-15% FBS  No    viral  OSKC  Yes  Yes  No  Yes  46,XX  DMEM/F12 + 20% KOSR + 1% non-essential AA + 1mM Gln + 0.1mM BME + 1% antibiotic/antimycotic on MEF  ~50  expansion  650  510  No  Yes  Dottori et al, Methods Mol Biol 438, p. 19, 2008.  no change    Tuj1+/MAP2+            Yes  GSE22651  Ku et al, Cell Stem Cell 7, p. 631, 2010.  PMID 21040903  joelg@scripps.edu; skusen@scripps.edu   
Click to Select 4078.1B3  Fibroblasts  Cell Repository  Coriell, GM04078  Patient  30  Male  Yes  Coriell  541  420  No    Yes  GM04079, B lymphoblast  ~10  Primary  MEM + 1% non-essential AA + 10-15% FBS   No    viral  OSKC  Yes  Yes  No  No    DMEM/F12 + 20% KOSR + 1% non-essential AA + 1mM Gln + 0.1mM BME + 1% antibiotic/antimycotic on MEF  ~50  expansion  730  550  No  Yes  Dottori et al, Methods Mol Biol 438, p. 19, 2008.  not analyzed                Yes  GSE22651  Ku et al, Cell Stem Cell 7, p. 631, 2010.  PMID 21040903  joelg@scripps.edu; skusen@scripps.edu